CAMBRIDGE, Mass. – October 22, 2020 – Nimbus Therapeutics, a biotechnology company designing breakthrough medicines through structure-based drug discovery and development, today announced the presentation of new data on the company’s novel hematopoietic progenitor kinase 1 (HPK1) inhibitors at upcoming scientific conferences.

At the 32^nd EORTC-NCI-AACR Symposium, from October 24-25, 2020, Nimbus will present new in vivo data, including target engagement, tumor growth inhibition, and pharmacodynamics in two mouse syngeneic tumor models (CT26 and B16/F10).

Further, at the Society for Immunotherapy of Cancer’s (SITC) 35^th Anniversary Annual Meeting, from November 9-14, 2020, Nimbus will present new data on in vitro pharmacology and mechanism of action of the HPK1 inhibitors, including effects on T cells, B cells, dendritic cells and antigen presentation.

“Building on the data we presented at AACR earlier this year, we’re pleased to share these new results which provide further support for the anti-tumor immune activity of our small-molecule HPK1 inhibitors,” said Peter Tummino, Ph.D., Chief Scientific Officer of Nimbus. “We are progressing towards initiation of IND-enabling studies in the near future, with plans to embark upon first-in-human studies of this novel therapeutic in 2021.”

Details of the presentations are as follows:

EORTC 2020: Pre-recorded presentation with live Q&A

• Title: “A Highly Selective and Potent HPK1 Inhibitor Enhances Immune Cell Activation and Induces Robust Tumor Growth Inhibition in a Murine Syngeneic Tumor Model”
• Presentation Number: PD-046
• Date & Time: Sun., Oct. 25, 2:50 p.m. CET (9:50 a.m. ET)

SITC 2020: Live presentation

• Title: “A Highly Selective and Potent HPK1 Inhibitor Enhances Immune Cell Activation and Induces Robust Tumor Growth Inhibition in a Murine Syngeneic Tumor Model”
• Poster Number: 685
• Dates & Times: Weds., Nov. 11, 5:15 p.m. ET; Fri., Nov. 13, 4:40 p.m. ET

About Nimbus Therapeutics

Nimbus Therapeutics designs breakthrough medicines. Utilizing its powerful structure-based drug discovery engine, Nimbus designs potent and selective small molecule compounds targeting proteins that are known to be fundamental drivers of pathology in highly prevalent human diseases and which have proven difficult for other drug makers to tackle. The company’s LLC/subsidiary architecture enables diverse and synergistic partnerships to deliver breakthrough medicines. Nimbus is headquartered in Cambridge, Mass. www.nimbustx.com.

Media Contact

Lisa Raffensperger, (617) 903-8783

Ten Bridge Communications

lisa@tenbridgecommunications.com

DOWNLOAD PRESS RELEASE

CAMBRIDGE, Mass. – October 19, 2020 – Nimbus Therapeutics, a biotechnology company designing breakthrough medicines through structure-based drug discovery and development, today announced the appointment of Erin Cowhig as Chief People Officer. In this newly created role, Ms. Cowhig will oversee all aspects of Nimbus’ human resources, talent acquisition and management, and diversity and inclusion efforts.

“Our people are the reason for Nimbus’ many years of success. With Erin’s leadership as Chief People Officer we are excited to further build our high-performing team, continuing to recruit talented and diverse new Nimbi, develop and invest in our people, and foster a values-driven culture,” said Jeb Keiper, M.S., MBA, Chief Executive Officer of Nimbus. “We’re very excited to welcome Erin to the Nimbus team and are confident that her deep experience in human resources, talent acquisition, and diversity and inclusion will contribute to driving Nimbus’ future success.”

Prior to joining Nimbus, Ms. Cowhig was Vice President, Human Resources at Vertex Pharmaceuticals, where she was responsible for HR governance, portfolio management, and organizational effectiveness as well as serving on Vertex’s HR leadership team. Ms. Cowhig was also responsible for leading Vertex’s Diversity and Inclusion strategy. Prior to Vertex, Ms. Cowhig was Senior Director and Head of Talent at Agios Pharmaceuticals, where she led talent acquisition and talent management efforts amidst the company’s transition from a research-focused organization to a late-stage development and commercial company. Ms. Cowhig holds a B.S. in human development and a Master of Industrial and Labor Relations, both from Cornell University.

“Nimbus’ community of passionate, talented people is an incredible asset, and it’s a team I feel privileged to join,” said Ms. Cowhig. “I’m excited to build upon the people-centric culture Nimbus has created to continue to make Nimbus a place of diverse, engaged, top-notch people who are empowered to do their best work and to make a difference in the lives of patients.”

About Nimbus Therapeutics

Nimbus Therapeutics designs breakthrough medicines. Utilizing its powerful structure-based drug discovery engine, Nimbus designs potent and selective small molecule compounds targeting proteins that are known to be fundamental drivers of pathology in highly prevalent human diseases and which have proven difficult for other drug makers to tackle. The company’s LLC/subsidiary architecture enables diverse and synergistic partnerships to deliver breakthrough medicines. Nimbus is headquartered in Cambridge, Mass. www.nimbustx.com.

Media Contact

Lisa Raffensperger, (617) 903-8783

Ten Bridge Communications

lisa@tenbridgecommunications.com

DOWNLOAD PRESS RELEASE

Leading life science investors RA Capital Management and BVF Partners L.P. join Nimbus investor base

CAMBRIDGE, Mass. – October 14, 2020 – Nimbus Therapeutics, a biotechnology company designing breakthrough medicines through structure-based drug discovery and development, today announced the close of a $60 million private financing round from life science investors RA Capital Management and BVF Partners L.P. (“RA” and “BVF”, respectively). The funds support the acceleration of Nimbus’ Phase 1 allosteric tyrosine kinase 2 (TYK2) inhibitor into Phase 2 early next year, its hematopoietic progenitor kinase 1 (HPK1) inhibitor into the clinic next year, as well as the advancement of its preclinical portfolio of new medicines.

“Today’s financing evidences the remarkable success of our structure-based drug discovery approach and the exciting data our pipeline has generated,” said Jeb Keiper, M.S., MBA, Chief Executive Officer of Nimbus. “This financing also defines a pathway for our future, and while we could not welcome all the investors with interest in Nimbus into this round, we expect with continued success to build on this financing by bringing on additional new investment in 2021.”

“Nimbus’ compelling TYK2 clinical data clearly positions us for a Phase 2b trial, which will generate data on the same endpoints as BMS’ TYK2 program,” said Bruce Booth, D.Phil., co-founder and Chairman of the Board of Nimbus. “We are fortunate to have RA and BVF join Nimbus, and we welcome Laura Stoppel from RA to the Board.”

“We’re proud to join Nimbus’ circle of investors and to lead this most recent financing round,” said Peter Kolchinsky, Ph.D., a founder and Managing Partner of RA Capital Management. “We see tremendous potential for Nimbus’ lead program, one of only two clinical allosteric approaches to TYK2 inhibition, and for the company’s newly added preclinical programs to address important therapeutic needs in oncology, immunology, and metabolism.”

About Nimbus Therapeutics

Nimbus Therapeutics designs breakthrough medicines. Utilizing its powerful structure-based drug discovery engine, Nimbus designs potent and selective small molecule compounds targeting proteins that are known to be fundamental drivers of pathology in highly prevalent human diseases and which have proven difficult for other drug makers to tackle. The company’s LLC/subsidiary architecture enables diverse and synergistic partnerships to deliver breakthrough medicines. Nimbus is headquartered in Cambridge, Mass. www.nimbustx.com.

Media Contact

Lisa Raffensperger, (617) 903-8783

Ten Bridge Communications

lisa@tenbridgecommunications.com

DOWNLOAD PRESS RELEASE

CAMBRIDGE, Mass. – September 28, 2020 – Nimbus Therapeutics, a biotechnology company designing breakthrough medicines through structure-based drug discovery and development, today announced the promotion of Abbas Kazimi to Chief Business Officer. Mr. Kazimi, who previously served as Vice President of Business Development, has more than 15 years of experience directing strategic transactions within the life sciences industry.

“Throughout his tenure with Nimbus, Abbas has played a central role in building our external partnerships, negotiating key transactions, and shaping our corporate strategy. We are exceptionally pleased to promote him to the role of Chief Business Officer,” said Jeb Keiper, M.S., MBA, Chief Executive Officer of Nimbus. “Abbas’ deep acumen in business and corporate development will be an asset for Nimbus as he moves into this expanded leadership role, and I look forward to continuing to partner with him to drive Nimbus’ success.”

Mr. Kazimi joined Nimbus in 2014 as Director of Business Development. In his roles at Nimbus, Mr. Kazimi drove several of the company’s transformative transactions, including the licensing agreement with Genentech in 2015, the sale of Nimbus’ clinical NASH program to Gilead up to an aggregate of $1.2 billion in 2016, and the strategic alliances with Celgene announced in 2017 and 2019. Prior to joining Nimbus, Mr. Kazimi spent a decade in planning and executing strategic transactions for life sciences clients with industry partners and financial investors across the globe. He earned his M.A. from Harvard University and his B.A. from the University of Texas at Austin.

About Nimbus Therapeutics

Nimbus Therapeutics designs breakthrough medicines. Utilizing its powerful structure-based drug discovery engine, Nimbus designs potent and selective small molecule compounds targeting proteins that are known to be fundamental drivers of pathology in highly prevalent human diseases and which have proven difficult for other drug makers to tackle. The company’s LLC/subsidiary architecture enables diverse and synergistic partnerships to deliver breakthrough medicines. Nimbus is headquartered in Cambridge, Mass. www.nimbustx.com.

Media Contact

Lisa Raffensperger, (617) 903-8783

Ten Bridge Communications

lisa@tenbridgecommunications.com

DOWNLOAD PRESS RELEASE

CAMBRIDGE, Mass. – September 1, 2020 – Nimbus Therapeutics, a biotechnology company designing breakthrough medicines through structure-based drug discovery and development, today announced that it has appointed Scott Edmondson, Ph.D., as Senior Vice President, Head of Chemistry. Dr. Edmondson’s accomplished tenure in the biopharma industry, most recently as the Director and Head of Boston Oncology Chemistry at AstraZeneca, will be an asset in Nimbus’ work to advance therapeutic candidates for its recently expanded portfolio of promising targets across oncology, immunology and metabolism.

“We’re delighted to welcome Scott to Nimbus at such an exciting period of growth for the company,” said Peter Tummino, Ph.D., Chief Scientific Officer of Nimbus. “Scott’s extensive experience at building and leading world-class chemistry teams will be incredibly valuable as we progress our discovery efforts and lay the groundwork for our next generation of important small molecule therapeutics.”

Prior to joining Nimbus, Dr. Edmondson was the Director and Head of Boston Oncology Chemistry at AstraZeneca. In that role he oversaw recruiting, management and strategic direction for a team of over 30 chemists as well as management of an external international team of chemists. Previously, Dr. Edmondson was at Merck for 18 years in positions of ascending leadership, culminating in his role as Director of Discovery Chemistry. Over the course of his career at Merck, he led multiple cross-functional and cross-site teams as well as external collaborations. Dr. Edmondson has co-authored more than 50 publications and 55 patents. He holds a B.A. in chemistry from Cornell University, a Ph.D. in synthetic organic chemistry from The Ohio State University and completed a postdoc at Columbia University as an NIH Postdoctoral Fellow.

“I’m excited to join this exceptional team of drug hunters,” said Dr. Edmondson. “Nimbus’ unique position at the nexus of structural biology, computational chemistry and molecular sciences has driven the company’s long history of successes, and I’m eager to help lead the discovery efforts that will shape the company’s promising future pipeline.”

About Nimbus Therapeutics

Nimbus Therapeutics designs breakthrough medicines. Utilizing its powerful structure-based drug discovery engine, Nimbus designs potent and selective small molecule compounds targeting proteins that are known to be fundamental drivers of pathology in highly prevalent human diseases and which have proven difficult for other drug makers to tackle. The company’s LLC/subsidiary architecture enables diverse and synergistic partnerships to deliver breakthrough medicines. Nimbus is headquartered in Cambridge, Mass. www.nimbustx.com.

Media Contact

Lisa Raffensperger, (617) 903-8783
Ten Bridge Communications
lisa@tenbridgecommunications.com

DOWNLOAD PRESS RELEASE

CAMBRIDGE, Mass. – June 22, 2020 – Nimbus Therapeutics, a biotechnology company designing breakthrough medicines through structure-based drug discovery and development, today presented a poster at the AACR Virtual Annual Meeting II detailing promising preclinical findings from the company’s HPK1 pipeline program.

Nimbus developed multiple selective small-molecule inhibitors of HPK1 using the company’s proven structure-based drug discovery engine. The lead compound, NMBS-1, displays very high selectivity against T cell-specific kinases and kinases in the MAP4K family and promising activity in in vitro and in vivo models. NMBS-1 enhanced IL-2 production from stimulated human T cells, alleviated PGE2-mediated immunosuppression of T cell activation, and enhanced IL-6 production, proliferation, and IgG secretion from B cells. In a mouse syngeneic tumor model, oral administration of NMBS-1 resulted in significant tumor growth inhibition, both as a monotherapy and in combination with anti-CTLA4.

“These data are further evidence that HPK1 inhibition is a potentially powerful approach to achieve anti-tumor immunity — and we’re very pleased that our small-molecule inhibitor displays the selectivity that has long been a challenge for drug makers in this space,” said Peter Tummino, Ph.D., Chief Scientific Officer of Nimbus. “We will continue rapidly advancing our preclinical studies, with the goal of initiating a first-in-human trial next year.”

The poster is titled “A Highly Selective and Potent HPK1 Inhibitor Enhances Immune Cell Activation and Induces Robust Tumor Growth Inhibition in a Syngeneic Tumor Model.”

 The company will be hosting a webcast to further discuss these data on Thursday, June 25, from 11 a.m. to 12 p.m. ET. If you wish to attend the live webcast, please pre-register at https://bit.ly/NimbusHPK1Seminar. A replay of the webcast will be available at this link after the event. 

About Nimbus Therapeutics 

Nimbus Therapeutics designs breakthrough medicines. Utilizing its powerful structure-based drug discovery engine, Nimbus designs potent and selective small molecule compounds targeting proteins that are known to be fundamental drivers of pathology in highly prevalent human diseases and which have proven difficult for other drug makers to tackle. The company’s LLC/subsidiary architecture enables diverse and synergistic partnerships to deliver breakthrough medicines. Nimbus is headquartered in Cambridge, Mass. www.nimbustx.com 

Media Contact

Lisa Raffensperger, (617) 903-8783
Ten Bridge Communications
lisa@tenbridgecommunications.com

DOWNLOAD PRESS RELEASE

CAMBRIDGE, Mass. – June 18, 2020 – Nimbus Therapeutics, a biotechnology company designing breakthrough medicines through structure-based drug discovery and development, will host a webcast seminar to discuss the latest data from its HPK1 program on Thursday, June 25, from 11 a.m. to 12 p.m. ET.

The seminar will feature presentations by Nimbus’ scientific leadership that give a brief overview of the company’s discovery pipeline and a deeper dive on data contained in the company’s poster presentation at the AACR Virtual Annual Meeting II, June 22-24. The included data detail Nimbus’ identification of an HPK1 inhibitor with highly potent and selective anti-tumor activity in preclinical models.

If you wish to attend the live webcast, please pre-register at https://bit.ly/NimbusHPK1Seminar. A replay of the webcast will be available at this link after the event.

About Nimbus Therapeutics 

Nimbus Therapeutics designs breakthrough medicines. Utilizing its powerful structure-based drug discovery engine, Nimbus designs potent and selective small molecule compounds targeting proteins that are known to be fundamental drivers of pathology in highly prevalent human diseases and which have proven difficult for other drug makers to tackle. The company’s LLC/subsidiary architecture enables diverse and synergistic partnerships to deliver breakthrough medicines. Nimbus is headquartered in Cambridge, Mass. www.nimbustx.com

Media Contact

Lisa Raffensperger, (617) 903-8783
Ten Bridge Communications
lisa@tenbridgecommunications.com

DOWNLOAD PRESS RELEASE

AMPKβ2, CTPS1, Cbl-b and WRN are highly promising targets for Nimbus’ structure-based drug discovery approach

CAMBRIDGE, Mass. – June 8, 2020 – Nimbus Therapeutics, a biotechnology company designing breakthrough medicines through structure-based drug discovery and development, announced the expansion of the company’s pipeline of small molecule candidates across a range of highly prevalent human diseases. These preclinical programs — AMPKβ2 (AMP-activated protein kinase, β2 subunit), CTPS1 (CTP synthase 1), Cbl-b (Cbl proto-oncogene B), and WRN (Werner syndrome ATP-dependent helicase) — represent promising targets across oncology, immunology and metabolism, for which Nimbus’ structure-based discovery approaches are uniquely suited.

“The additional programs we’re unveiling today are a testament to Nimbus’ exceptional talent, the unwavering support of our investors, and the dynamic scientific collaborations we have built over the past decade,” said Jeb Keiper, M.S., MBA, Chief Executive Officer of Nimbus. “Our prolific pipeline reflects the breadth of potential we see for our discovery engine going forward, and a new chapter in Nimbus’ leadership of structure-based drug discovery. We look forward to progressing these programs forward to the clinic within our development organization, which advanced our ACC inhibitor to an early proof of mechanism and is currently progressing our Tyk2 inhibitor toward Phase II.”

“With the addition of these targets, we’ve built a pipeline of promising therapeutics for the treatment of patients with diseases that have limited or no therapeutic options,” said Peter Tummino, Ph.D., Chief Scientific Officer of Nimbus. “Each of these targets represents the ‘sweet spot’ for Nimbus’ approach — they are known to be fundamental drivers of highly prevalent diseases but have proven difficult for the industry to drug. As we have demonstrated with our progress on HPK1, which is being presented at AACR this month, we believe our structure-based drug discovery engine can generate the potent, selective small molecule therapeutics needed to move the needle on these targets.”

A brief overview of our newly disclosed programs follows:

• AMPKβ2 for cellular metabolic regulation
  AMPK is a kinase that serves as a critical regulator of energy-sensing and metabolic homeostasis in many tissues. Small molecule activation of AMPK has long been recognized as a potential strategy to treat multiple metabolic disorders and other pathologies. Nimbus’ approach leverages new understandings in AMPK subunit structure to identify activators selective for the AMPKβ2 subtype of the protein to improve glucose and lipid homeostasis, while reducing undesired effects.

• CTPS1 for controlling immune activation
  CTPS1 is a key enzyme in the pyrimidine synthesis pathway in lymphocytes, making it a drug target for autoimmune diseases and cancer. Selective inhibitors of CTPS1 hold promise for attenuating lymphocyte proliferation and providing effective treatments for T and B cell-driven diseases. Nimbus is using structure-based and other computational chemistry approaches to identify small molecules that are highly potent inhibitors of CTPS1 with selectivity over CTPS2.

• Cbl-b for enhancing immune sensitivity in cancer
  Cbl-b is an E3 ubiquitin ligase that directs the degradation of signaling proteins across a variety of immune cells. Cbl-b is a well-validated immuno-oncology target, given that Cbl-b knockout mice spontaneously reject tumors with enhanced T and NK cell responses, and Cbl-b deficient T cells can be activated in the absence of co-stimulatory signals. Nimbus is pursuing a structure-based approach to designing inhibitors of Cbl-b that can enhance anti-tumor immunity.

• WRN as a selective approach to targeting MSI-high tumors
  WRN, a helicase required for DNA replication and repair, is a validated target for treating microsatellite-instability high tumors (“MSI-H tumors”). Pharmacological inhibition of helicases has proven difficult in the past, but WRN is now amenable to structural biology approaches, allowing Nimbus to design both active-site and allosteric inhibitors of WRN that should induce synthetic lethality in tumors with microsatellite instability. 

About Nimbus Therapeutics 

Nimbus Therapeutics designs breakthrough medicines. Utilizing its powerful structure-based drug discovery engine, Nimbus designs potent and selective small molecule compounds targeting proteins that are known to be fundamental drivers of pathology in highly prevalent human diseases and which have proven difficult for other drug makers to tackle. The company’s LLC/subsidiary architecture enables diverse and synergistic partnerships to deliver breakthrough medicines. Nimbus is headquartered in Cambridge, Mass. www.nimbustx.com

Media Contact

Lisa Raffensperger, (617) 903-8783
Ten Bridge Communications
lisa@tenbridgecommunications.com

DOWNLOAD PRESS RELEASE

CAMBRIDGE, Mass. – May 29, 2020 – Nimbus Therapeutics, a biotechnology company designing breakthrough medicines through structure-based drug discovery and development, today announced the promotion of Alan Collis, Ph.D., to Senior Vice President, Preclinical Development.

“Alan’s leadership has been integral to the robust progress of Nimbus’ pipeline in recent years, including the successful completion of preclinical development of our Tyk2 allosteric inhibitor, and the generation of promising preclinical data from our HPK1 program, which will be showcased at the AACR Virtual Annual Meeting next month,” said Peter J. Tummino, Ph.D., Chief Scientific Officer of Nimbus. “Additionally, Nimbus will soon be announcing new preclinical programs for a number of valuable targets, and we’re excited that this expanded pipeline will continue to benefit from Alan’s broad expertise and leadership.”

“Nimbus’ success is a product not just of our structure-based drug discovery platform, but the powerful combination of that technology with our team’s deep expertise in biopharmaceutical drug development. Alan’s impact at Nimbus perfectly reflects the two successfully coming together,” said Annie C. Chen, M.D., MPH, Chief Medical Officer of Nimbus and President of the company’s Tyk2 subsidiary, Nimbus Lakshmi, Inc. “We heartily congratulate him on this well-deserved promotion.”

Dr. Collis joined Nimbus in 2018 to lead the company’s Tyk2 program, and was appointed Vice President, Preclinical Development, in early 2019. Prior to joining Nimbus, he was Executive Director of DMPK at Forma Therapeutics, in which role he transitioned two projects into Phase II, four through IND, and five through preclinical profiling. Before that, Dr. Collis served as Novartis’ Executive Director of Scientific and Strategic Planning and Global Leader of the Metabolism and Pharmacokinetics group. In that role, he advised on all aspects of project strategy, compound progression, and business planning. Earlier in his career, Dr. Collis held significant leadership roles in medicinal chemistry in the large pharma settings of Aventis, Rhone-Poulenc Rorer, and Pfizer.

About Nimbus Therapeutics

Nimbus Therapeutics designs breakthrough medicines. Utilizing its powerful structure-based drug discovery engine, Nimbus designs potent and selective small molecule compounds targeting proteins that are known to be fundamental drivers of pathology in highly prevalent human diseases and which have proven difficult for other drug makers to tackle. The company’s LLC/subsidiary architecture enables diverse and synergistic partnerships to deliver breakthrough medicines. Nimbus is headquartered in Cambridge, Mass. www.nimbustx.com

Media Contact

Lisa Raffensperger, (617) 903-8783
Ten Bridge Communications
lisa@tenbridgecommunications.com

 

DOWNLOAD PRESS RELEASE

Data to be presented at 2020 AACR Annual Meeting show HPK1 inhibition produced robust anti-tumor response in mouse model

CAMBRIDGE, Mass. – May 15, 2020 – Nimbus Therapeutics, a biotechnology company designing breakthrough medicines through structure-based drug discovery and development, today announced the identification of an HPK1 inhibitor with highly potent and selective anti-tumor activity in preclinical models. The data will be presented at the AACR Virtual Annual Meeting II, June 22-24, 2020.

HPK1 (hematopoietic progenitor kinase 1) is a highly valued target in immuno-oncology due to its role as a regulator of both T cell and dendritic cell activity. However, a key challenge for development of small molecules acting on HPK1 has been to achieve selectivity against other T cell kinases and MAP4K family members. Nimbus utilized its unique structure-based drug discovery engine to identify multiple potent and selective small molecule inhibitors of HPK1. One of these molecules, advanced to in vivo testing, has high selectivity against T cell-specific kinases and kinases in the MAP4K family and exhibits promising activation of human T cells and B cells. In a mouse syngeneic tumor model, oral administration of the HPK1 inhibitor completely eliminated HPK1’s phosphorylation of the T cell receptor, enhanced inflammatory cytokine production, and demonstrated robust tumor growth inhibition.

“We’re excited to pull back the curtain on Nimbus’ HPK1 program and share some of the progress we’ve made against a target that has evaded so many others’ efforts,” said Jeb Keiper, M.S., MBA, Chief Executive Officer of Nimbus. “Nimbus’ unparalleled expertise in structure-based drug discovery allowed us to chart an entirely new approach to inhibiting HPK1. In addition, we have recently leveraged this approach to generate small molecules against a range of promising new targets, and we look forward to sharing details on these programs in the coming weeks.”

“These data support the potential of our HPK1 inhibitor to alter the tumor microenvironment to halt cancer’s immune evasion, which we think could be a powerful tool in today’s immuno-oncology arsenal,” said Peter Tummino, Ph.D., Chief Scientific Officer of Nimbus. “We are advancing this program into IND-enabling studies, with the goal of entering the clinic next year, and ultimately providing a new therapeutic approach to address the large unmet need among patients with cancer.” 

About Nimbus Therapeutics 

Nimbus Therapeutics designs breakthrough medicines. Utilizing its powerful structure-based drug discovery engine, Nimbus designs potent and selective small molecule compounds targeting proteins that are known to be fundamental drivers of pathology in highly prevalent human diseases and which have proven difficult for other drug makers to tackle. The company’s LLC/subsidiary architecture enables diverse and synergistic partnerships to deliver breakthrough medicines. Nimbus is headquartered in Cambridge, Mass. www.nimbustx.com

Media Contact

Lisa Raffensperger, (617) 903-8783
Ten Bridge Communications
lisa@tenbridgecommunications.com

 

DOWNLOAD PRESS RELEASE